Psychomotor impairment Like other sedative/hypnotic medications, zopiclone has CNS-depressant effects. The chance of psychomotor impairment, which includes impaired driving potential, is enhanced if: zopiclone is taken in 12 hours of carrying out activities that call for mental alertness, a dose increased than the recommended dose is taken, or zopi

Hepatic impairment: The dosage really should be changed in patients with hepatic impairment, as zolpidem's fifty percent-existence was repeatedly lengthier than in individuals with regular liver purpose. Like other phenanthrene derivatives, dihydrocodeine is mainly metabolised inside the liver with the resultant metabolites being excreted primar

Bodily dependence is actually a point out that develops due to a physiological adaptation in reaction to recurring drug use, manifested by withdrawal symptoms and signs or symptoms just after abrupt discontinuation or a big dose reduction of a drug.Codeine sulfate tablets may perhaps impair the psychological or Bodily qualities necessary to accompl